Installation

1. 1
   Make sure Claude is on your device and in your terminal.

   Skills load from ~/.claude/skills/ when Claude Code starts up — so you need it on your machine first. If you don't have it yet, install it once with the command below, then run claude in any terminal to verify.

   One-time setup

   Copy

   npm i -g @anthropic-ai/claude-code

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2. 2
   Paste into Claude Code or into your terminal.

   Install

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   This copies the whole skill folder into ~/.claude/skills/borzoi-aipoch/ — the SKILL.md plus any scripts, reference docs, or templates the skill ships with. Safe default: works for every skill.

   Faster alternative (instruction-only skills)

   Skips the clone and grabs only the SKILL.md file. Don't use this if the skill ships Python scripts, reference markdowns, or asset templates — they won't be downloaded and the skill will fail when it tries to load them.

   Quick install (SKILL.md only)

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   mkdir -p ~/.••••••••••••••••••••••••••• •• •••• ••••• ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• •• •••••••••••••••••••••••••••••••••••••••

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3. 3
   Restart Claude Code.

   Quit and reopen Claude Code (or any other agent that loads from ~/.claude/skills/). New skills are picked up on startup.

4. 4
   Just ask Claude.

   Skills auto-activate when your request matches the skill's description — no slash command needed. Trigger phrases live in the skill's own frontmatter; you can read them in the “What this skill does” section above.

Prefer to read the source first? Open on GitHub.

When Claude uses it

Predict genome-wide functional tracks (RNA-seq, CAGE, DNase, ChIP) from DNA sequence with Borzoi. Use this skill when: (1) Scoring the regulatory effect of a variant on expression/accessibility, (2) Generating predicted coverage tracks for a locus, (3) Prioritising non-coding variants by predicted track delta.

What this skill does

from borzoi_pytorch import Borzoi

model = Borzoi.from_pretrained("johahi/borzoi-replicate-0").cuda().eval()
# input: (batch, 4, 524288) one-hot DNA  → output: (batch, tracks, 6144) bins

c = host.compute.create(provider)
job = c.submitJob(
    intent="Borzoi track prediction for 1 locus — 1×GPU, ~2 min",
    inputs=[{"src": "borzoi_run.py", "dstFilename": "borzoi_run.py"}],
    command="python3 borzoi_run.py",   # env selection is host-specific — see compute_details for your provider
    outputs=["tracks.npz"],
    timeoutSeconds=1800,
)
print(job.job_id)   # cell ends here — kernel never blocks on compute